After arriving at Ohio University in 1966, Gene Thrailkill made drastic changes to the Ohio University Marching Band. While there were some controversial changes having to do with membership, he ultimately hoped to increase the band's size from approximately 85 members. The following fall, 112 marchers were chosen to march in the new band. This 112 is still evident in the band's pre-game show. Other changes included new traditional uniforms and a new style for the band. With popular music of the day, hard-driving marching and a great "esprit-de-corps," the 110 Marching Men of Ohio began "The Most Exciting Band in the Land." Thrailkill was also the originator of the 110's "Diamond Ohio" formation. Thrailkill pushed for the "Diamond Ohio" formation to give the band its own trademark. Thrailkill was director of bands until 1971.

Prior to his arrival to Ohio University in 1966, Thrailkill served as director of instrumental music for the New Lebanon Public Schools (Ohio). He holds a Bachelor of Music degree from the University of Michigan and a Master of Music degree from Ohio University. In 2000 Coach Thrailkill retired as Regents Professor and Professor of Music at The University of Oklahoma where he took over in 1971. He also served as Director of University Bands and headed the extensive OU band program.

The Marching 110 was honored to have Mr. Thrailkill speak and guest conduct the 110 at Homecoming 2001. Mr. Thrailkill attended the Thursday, Friday and Saturday morning practices of the Marching 110, as well as the new OUMB Society of Alumni & Friends Display Case dedication ceremony in Memorial Auditorium.